Clinical Trials and Ovarian Cancer
★ Why And When To Enter A Clinical Trial?
For ovarian cancer patients, clinical trials can be an option at the beginning of treatment as well as later on in the event of recurrence. It is worth noting that many clinical trial protocols limit the number of rounds and types of chemotherapy previously taken.
Clinical trials or clinical research studies involve testing the effectiveness of new drugs for cancer (and other illnesses) on human subjects.
Participating in a clinical trial helps to further the field of cancer treatment and provides patients the opportunity to try medications that might be effective against their disease.
University of Colorado Cancer Center
Colorado’s only National Cancer Institute (NCI)-Designated Cancer Center
Phone: 720.848.0300
“The University of Colorado Cancer Center in Denver is one of just 45 elite Comprehensive Cancer Centers in the entire country and the only one in Colorado. We're known worldwide for developing and setting new standards in the treatment of many types of cancer. Our 5-year cancer outcomes far outpace state averages as well as those of many other cancer centers in the U.S.”
https://www.cancer.gov/research/nci-role/cancer-centers/find/ucolorado
To find Clinical Trials currently being offered at CU Cancer Center:
http://www.ucdenver.edu/academics/colleges/medicalschool/centers/cancercenter/clinicaltrials/Pages/ClinicalTrials.aspx
https://medschool.cuanschutz.edu/colorado-cancer-center/clinical-trials/ccto-team
Sarah Cannon Research Institutes
asksarah@sarahcannon.com
303.253.3225
“Sarah Cannon and the HealthONE Family of Hospitals in Denver, Colo. are fighting cancer together to offer patients cutting-edge clinical research alongside integrated cancer services from discovery to recovery. “
North Suburban Medical Center, Thornton - 303-451-7800
Presbyterian/St. Luke's Medical Center - 303-839-6000
Red Rocks Cancer Center - 303-940-8200
Rose Medical Center - 303-320-2121
Sarah Cannon Research Institute at HealthONE - 720-754-2610
Sky Ridge Medical Center - 720-225-1000
Swedish Medical Center - 303-788-5000
The Medical Center of Aurora - 303-695-2600
https://sarahcannon.com/locations/
ClinicalTrials.gov
“ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.”
U. S. National Institutes of Health (NIH)
“The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses.” Information about clinical trials can be found at:
https://www.nih.gov/health-information/nih-clinical-research-trials-you
EmergingMed Navigator
“EmergingMed’s Clinical Trial Navigators provide concierge support to patients and physicians searching for clinical trial opportunities that match a patient’s specific diagnosis, symptoms or stage, and treatment history.”
1.877.601.8601
9:00am - 5:00pm ET (M-F)
https://app2.emergingmed.com/emed/home
The Clearity Foundation
“The Clearity foundation is committed to science, devoted to patients, Clearity is your trusted partner for the ovarian cancer journey.”
https://forms.clearityfoundation.org/find-clinical-trials/
★ Clinical trial drugs are paid for by the research study, and Colorado law requires insurance to cover routine patient care costs in clinical trials. Check with your insurer about any additional costs of required scans and blood tests.
COCA may help pay for transportation to a clinical trial. See COCACares.
Clinical Trial Phases
Phase 0 - Exploratory study involving very limited human exposure to the drug, with no therapeutic or diagnostic goals (for example, screening studies, microdose studies).
Phase 1 - Studies that are usually conducted with healthy volunteers and that emphasize safety. The goal is to find out what the drug’s most frequent and serious adverse events are and, often, how the drug is metabolized and excreted.
Phase 2 - Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition). For example, participants receiving the drug may be compared with similar participants receiving a different treatment, usually an inactive substance (called a placebo) or a different drug. Safety continues to be evaluated, and short-term adverse events are studied.
Phase 3 - Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.
Phase 4 - Studies occurring after the FDA has approved a drug for marketing. These including postmarket requirement and commitment studies that are required of or agreed to by the sponsor. These studies gather additional information about a drug’s safety, efficacy, or optimal use.”
https://clinicaltrials.gov/ct2/help/glossary/phase